No-Shpa is intended to eliminate painful sensations and is considered an absolutely harmless drug that can be taken during pregnancy. Despite this, before using the drug No-Shpa during pregnancy, you should consult a doctor, since even this safe drug There are special indications, a number of contraindications and side effects.

General characteristics of the drug

No-Shpa contains drotaverine. This active component is an antispasmodic with myotropic action, that is, the substance interacts with the smooth muscles of the hollow internal organs- stomach, intestines, uterus and others. Under the influence of No-Shpa, the muscular membrane of the organs relaxes, thereby relieving the spasm, and the pain weakens or disappears completely.

In addition, under the influence of drotaverine, the smooth muscles of blood vessels also relax, due to which they expand, and blood pressure moderately decreases. The direct myotropic effect in this case is an undoubted advantage, since the drug does not affect the central and peripheral nervous system. As a result, No-Shpa during pregnancy is recognized as a safe remedy, which also has a fairly long-lasting antispasmodic effect. The drug is more effective than Papaverine and other analogues.

Indications for use

Most often, No-Shpa is prescribed during pregnancy as part of a complex treatment. The drug is used to relieve spastic pain in the following pathologies:

1. spasms of cerebral vessels;
2. exacerbation of chronic inflammation of the mucous membrane of the stomach and duodenum (gastroduodenitis);
3. exacerbation of chronic gastric and duodenal ulcers;
4. inflammation in the large intestine (colitis, proctitis);
5. colic of various origins in the small and large intestines;
6. impaired motility of the bile ducts (various dyskinesias);
7. exacerbation of chronic cholecystitis (excluding calculous cholecystitis);
8. inflammatory processes of the renal pyelocaliceal apparatus (pyelitis);
9. kidney stones (nephrolithiasis).

No-Spa can be used after surgical procedures to relieve spasms. During childbirth, the use of No-Shpa can reduce cervical spasm. If childbirth is preceded by a pathological preliminary period, No-Shpa during pregnancy will help reduce the frequency and intensity of uterine contractions.

Contraindications

No-Spa during pregnancy is not allowed for use with the following complications:

• hypersensitivity to the composition of the drug;
• severe forms of heart, liver or kidney failure;
• hypersensitivity to sodium disulfide. This substance is contained in No-Shpa preparations intended for intravenous and intramuscular administration;
• hereditary galactose intolerance. Also, No-Shpa during pregnancy is contraindicated in cases of lactase enzyme deficiency or glucose-galactose malabsorption syndrome. This item applies to No-Shpa tablets, which contain lactose as an auxiliary component.

Patients with vegetative-vascular dystonia in combination with low blood pressure should use the drug with caution. If the expectant mother experiences hypotension, she should lie down during the injection to prevent the development of collapse.

Pregnant women who are known to be lactose intolerant may experience digestive system upset when taking No-Shpa tablets.

In case of lactase deficiency (deficiency of the enzyme responsible for the absorption of milk sugar - lactose), treatment with tablets is not allowed.

Thus, in case of disturbances in the absorption of glucose and galactose, No-Shpu is recommended to be administered intravenously, intramuscularly or rectally.

The body's increased sensitivity to sodium disulfide may lead to an allergic reaction in the form of bronchospasm when taking No-Shpa during pregnancy. Therefore, if there is a history of allergies, the use of the drug is excluded. In addition, the patient may have bronchial asthma as a contraindication.

Side effects

After taking No-Shpa, the following effects occur extremely rarely:

1. disruptions of the nervous system (dizziness, headaches, sleep disturbances);
2. malfunctions of cardio-vascular system(increased heartbeat, decreased blood pressure);
3. gastrointestinal problems (nausea, constipation);
4. allergic reactions (rash, itching, urticaria, Quincke's edema).

Overdose

Very few cases of overdose with drotaverine drugs have been recorded. In most cases, these are suicide attempts by patients caused by psychological problems using critical doses of No-Shpa. In some cases, an overdose is due to the fact that the drug was not taken according to instructions.

Typical manifestations of an overdose of No-Spa:

• vomiting, nausea, general malaise, constipation, intestinal obstruction;
• severe pain in the sternum, loss of consciousness caused by severe heart rhythm disturbances (including complete atrioventricular block);
• breathing disorders up to complete stop due to toxic effects on the respiratory center in the brain.

At the first signs of an overdose, it is necessary to immediately perform gastric lavage. To do this, you need to drink a few glasses of clean water and induce vomiting. An overdose of the drug No-Shpa during pregnancy is treated only in an inpatient setting in the intensive care unit.

Drug interactions

When taking different antispasmodic drugs simultaneously, their effect is enhanced.

No-Shpa injections during pregnancy can enhance the decrease in blood pressure if it is caused by taking tricyclic antidepressants, quinidine or procainamide.

Is it possible to drink No-Shpa during early pregnancy?

The most significant stage in fetal development is the first months of pregnancy, when the formation of the main organ systems and tissues of the body occurs. At this time, it is very important for the expectant mother to monitor her well-being, promptly contacting a doctor if any unpleasant symptoms appear.

No-Spa during pregnancy early stages is prescribed to relieve spasm of the smooth muscle fibers of the uterine walls. According to statistics, this phenomenon is the most common reason miscarriage. The active components of the drug relax the smooth muscle fibers of the myometrium (muscular layer of the uterus), restoring its tone. This contributes to the formation healthy conditions for the development of the child, therefore No-Shpa during pregnancy is widely used in the first trimester and in the first weeks of the second trimester.

No-Shpa during late pregnancy

The situation changes in the later stages of pregnancy. No-Spa during pregnancy later prescribed with caution. The main task is to maintain pregnancy and bring it to physiological terms. Therefore, drugs that can cause preterm labor should be used rarely or not at all.

Taking any medications has its own side effects. But if in ordinary life it’s easy to come to terms with this, then during pregnancy the situation changes dramatically. Many women are wary of taking medications – and for good reason. There are only a small number of medications that a woman can use during this period without fear of harming the baby. These include No-shpa. This antispasmodic is not only harmless, but in some cases it is necessary for a successful pregnancy. Since the drug is sold in pharmacies without a doctor’s prescription, and it is not at all difficult to purchase it, No-shpa has long become an integral element in any woman’s medicine cabinet.

The main indication for the use of the drug is to increase the muscle tone of the uterus. This condition is often characterized by pain in the lower abdomen or a feeling of hardness. Sometimes the disease is accompanied by bleeding. Often the cause of this disease is stress and overwork, excessive physical activity, as well as cases when a woman is expecting twins or triplets.

Petrification of the uterus can lead to complications, including premature birth. In addition, when muscles contract, the access of oxygen and other essential nutrients to the fetus is blocked. Lack of oxygen to the baby’s brain can subsequently lead to diseases of his central nervous system, as well as mental illness. Uterine tone is an extremely dangerous condition for a child, and in this case it is difficult to manage without the use of medications.

This is precisely why doctors prescribe No-shpa to women facing this problem. No-spa helps relieve muscle tension and dilate blood vessels. The drug is easily distributed in tissues, absorbed into the blood and completely eliminated from the body within three days, having completed its task.

In addition, No-shpa can be used directly during childbirth to accelerate the dilatation of the cervix. Also, it is prescribed by a doctor in a situation where the birth did not take place on the scheduled date, and the woman risks carrying the child. The drug has a softening effect on the cervix and promotes its rapid maturation. No-shpa is also used to relieve pain during contractions - in this case, the required dose is determined by the obstetrician.

Less commonly, the drug can be prescribed by a doctor if a woman experiences other pathologies not directly related to pregnancy, namely:

• diseases of the digestive system;
• diseases of the genitourinary system;
• cardiovascular diseases.

However, for headaches, No-shpu should be used with caution. If the cause of this condition was not spasms, but migraine, the drug will not only not help, but will also worsen the situation.

Is it possible to use No-shpa without a doctor’s prescription?

Self-administration of the drug is possible only if the doctor gave such a recommendation during previous examinations. The fact is that the pain that occurs during pregnancy is not always spasmodic in nature, and does not always carry a threat of termination of pregnancy. In some cases, it may be due to ordinary fatigue or anxiety. Breathing exercises, rest, and a walk in the fresh air will help relieve such pain. In some cases, it is worth reviewing your diet and eliminating foods that contribute to heartburn. Acute pain can be a symptom of non-pregnancy conditions such as appendicitis or ulcers.

One way or another, one cannot talk about the effectiveness of treatment with No-shpa without knowing exactly the essence of the ailment. If a woman understands medicine and is able to independently determine the cause of pain, taking the drug is possible. Otherwise, it is better not to take unnecessary risks, but to find out about the real state of your health in antenatal clinic. Gynecologists often discuss the possibility of spasmodic pain, as well as medications acceptable to relieve it.

If the woman has not yet seen a doctor, or the pain has arisen for the first time, independent use of any medications is excluded. In this case, you should immediately come for a consultation, and if the pain is too severe, call ambulance.

Even such a safe antispasmodic as No-shpa is undesirable to take in vain. But if due to circumstances it is not possible to immediately consult a doctor, and the pain becomes unbearable, you can take No-shpa in a small dosage. And yet, the sooner a woman visits a doctor if she feels unwell, the better.

Dosage of the drug

For each woman and each individual situation, the doctor prescribes an individual treatment schedule. This is due to the individual characteristics of the body and specific indications. There are two forms of taking No-shpa - in the form of tablets and injections. During pregnancy, the first type is usually used. Most often, No-shpa is taken 3 times a day - in the morning, at lunch and during dinner - 1-2 tablets. The maximum daily dose of the drug is 6 tablets. Typically, relief or complete disappearance of symptoms occurs within 1-3 days, after which the medication can be discontinued. But if the treatment does not have an effect and the spasms do not subside, the woman will need a second consultation and a different dosage schedule. In some cases, the patient will be recommended a different drug.

If No-shpa is used in preparation or during childbirth, doctors most often prescribe intravenous or intramuscular injections. This form is more effective and faster than tablets. The drug is administered intramuscularly to a woman in labor in an amount of 80 mg. A second injection can be given no earlier than two hours later.

Side effects

As with any other drug, taking No-shpa may have its own Negative consequences, such as:

• increased heart rate;
• general weakness and dizziness;
• low pressure;
• nausea;
• constipation

Separately, individual intolerance to the drug should be highlighted due to an allergy to one or another component. However, in case allergic reaction caused by the lactose contained in the tablets, No-shpu can be used in the form of injections. Ampoules of the drug do not contain this substance.

• hypotension;
• renal and liver failure;
• heart diseases;
• isthmic-cervical insufficiency (during pregnancy).

Can the use of No-shpa have a negative impact on the child?

This drug is absolutely safe for the fetus. This has been confirmed by multiple studies by scientists in which many women from different countries peace. Examinations of the newborn babies did not reveal any health problems. Experts consider the effect of No-shpa to be more effective and long-lasting than other antispasmodics. At the same time, we should not forget that any drug can be dangerous if used incorrectly. That is why it is important to strictly adhere to the doctor’s recommendations.

Video - taking medications during pregnancy and breastfeeding - School of Dr. Komarovsky

Among medicines, which are widely used during pregnancy, No-Shpa occupies a special position. Being a powerful antispasmodic, this drug eliminates any unpleasant and painful sensations associated with temporary dysfunction of the gastrointestinal tract in expectant mothers. Moreover, No-Shpa is absolutely safe during pregnancy; you can take it without any fear for your baby.

However, even with such a harmless drug, caution should be exercised, since this drug has its own indications, contraindications and side effects.

The active component of No-Shpa is drotaverine, a strong antispasmodic with myotropic action. This means that this drug directly affects the smooth muscle fibers that are located in the wall of hollow organs, such as the stomach, intestines, uterus, ureter and many others. As a result of taking No-Shpa, the muscular membrane of these organs relaxes and spasms are relieved, which leads to a decrease or disappearance of pain.

Unlike centrally acting muscle relaxants, which also relieve spasm of smooth muscles, No-Shpa does not affect the central and peripheral nervous system at all, and therefore does not cause such serious side effects as, for example, respiratory depression due to paralysis of the diaphragm. As a result, No-Shpu is often prescribed as the drug of choice for gastrointestinal, urological, gynecological diseases, as well as during pregnancy.

It should be borne in mind that due to its systemic effect on smooth muscles, No-Shpa also affects the functioning of the cardiovascular system. By relaxing small peripheral vessels, the drug leads to a slight decrease in blood pressure, which should be kept in mind in patients prone to hypotension. However, this effect of the drug is not so pronounced, and blood pressure can drop only when taking large doses.

Indications for use

In accordance with the instructions for use of the drug, No-Shpa is used for a number of diseases and pathological conditions accompanied by spasm of smooth muscles. It is especially often used for abdominal pain, since conventional painkillers are not recommended in this case.

Indications for use of No-Shpy:

• Biliary dyskinesia.
• Intestinal colic.
• Urolithiasis and renal colic.
• Chronic cholecystitis, cholelithiasis and hepatic colic.
• and the threat of premature birth.

The last indication is most consistent with obstetric and gynecological practice. Indeed, at the first signs of premature birth or threatened miscarriage, such as nagging pain in the lower abdomen and a feeling of fullness in this area, a single dose of No-Shpa in most cases helps to completely eliminate uterine hypertonicity and maintain pregnancy.

Another indication for the use of No-Shpa is spasm of the smooth muscles of the uterus and cervix during childbirth. This situation is dangerous because the child is as if in a vice - overly tense myometrial muscles try to expel him from the uterine cavity, but the contracted cervix prevents the fetus from moving along the birth canal. Often, one dropper with drotaverine is enough to restore normal labor.

Contraindications

Due to the systemic effect on the smooth muscles of internal organs, No-Shpa can lead to a number of undesirable consequences.

• Hypersensitivity to the components of the drug. If, after taking No-Shpa, such phenomena as urticaria, loss of consciousness, swelling of the lips and tongue, or a drop in blood pressure occurred at least once in your life, then for the sake of preserving the life and health of both yourself and your child, future mom should categorically refuse to take this drug.
• Glaucoma. Drotaverine can increase intraocular pressure, which can provoke an acute attack of glaucoma and temporary loss of vision in susceptible individuals.
• Heart rhythm disturbances and severe heart failure. Large doses of No-Shpa have an adverse effect on the functioning of the heart, so patients with cardiovascular diseases should take this drug with caution and only on the recommendation of a doctor.

If a pregnant woman suffers from lactase deficiency or other enzymatic disorders of the gastrointestinal tract, then she should not take No-Shpa in tablet form, since they contain lactose and galactose.

Side effects and adverse events

When using No-Shpa during pregnancy, side effects are observed extremely rarely - in less than 1 patient out of 1000.

Undesirable effects include:

• Tachycardia, or increased heart rate and pulse.
• Headache, dizziness (due to cerebral vasodilation).
• Nausea, very rarely - vomiting.
• Retention of stool and.

As a rule, these reactions occur when the dosage and instructions for use of No-Shpa during pregnancy are not followed - taking large doses of the drug with the hope of achieving a more lasting antispasmodic and analgesic effect. In many cases, this is completely unnecessary, and taking even one standard dose of No-Shpa helps to completely eliminate unpleasant symptoms.

Overdose

Cases of overdose with drotaverine are extremely rare. For the most part, this is due to psychological problems, when patients take critical doses of No-Shpa for the purpose of suicide, or without knowing the instructions for use.

Leading manifestations of No-Spa overdose during pregnancy:

• General malaise, nausea, vomiting, stool retention and even intestinal obstruction.
• Severe chest pain and loss of consciousness caused by severe cardiac conduction disturbances, including the development of complete atrioventricular block.
• Respiratory depression up to its complete stop due to a toxic effect on the respiratory center of the brain.

When the first signs of overdose appear, you should immediately drink several glasses of water and induce vomiting. Treatment of patients with an overdose of No-Spa, especially during pregnancy, is carried out only in a hospital in the intensive care unit.

Use of No-Shpa in early pregnancy

– the most critical stage of fetal development, when all the main organs and systems are formed. That is why the expectant mother should carefully monitor her health and promptly consult a doctor if the slightest unpleasant symptoms appear.

No-Spa during early pregnancy is prescribed to eliminate spasm of the smooth muscles of the uterus, which is the leading cause of miscarriages. The drug relaxes smooth muscle cells located in the myometrium (the muscular lining of the uterus), restoring its tone. This ensures normal conditions for the full development of the fetus, and therefore the drug is widely used during pregnancy in the 1st trimester, No-Shpu is also taken in the 2nd trimester - but no later than in the first two weeks.

Use of the drug in late pregnancy

The situation is different with No-Spa in the 2nd and 3rd trimesters of pregnancy, when it is prescribed with great caution. During these periods, the most important task of the doctor is to maintain the pregnancy and bring it to physiological terms, therefore drugs that can provoke premature birth are rarely used or not used at all.

The use of No-Shpa during late pregnancy also helps to relax the smooth muscles of the uterus, but, in addition, the drug acts directly on the muscular elements of the cervix. As a result, its spontaneous disclosure may occur, which can start the process. For this reason, No-Shpa during pregnancy in the 2nd and 3rd trimesters is used only in exceptional cases. Most often, No-shpu is prescribed at 39 weeks of pregnancy.

Use of the drug before childbirth

Drotaverine is often used to facilitate labor, in particular, to eliminate uterine hypertonicity. Some women in labor are prescribed standard doses of No-Shpa during pregnancy before giving birth, which help normalize the tone of the reproductive organ and ensure the dilation of its cervix. If hypertonicity occurs directly during childbirth, then a dropper with drotaverine or a simple intravenous injection of No-Shpa can completely eliminate this condition.

It is dangerous to take No-Shpu in the third trimester of pregnancy, as one of its possible side effects is uterine hypotension. In this situation, there may be a delay in the separation of the placenta and even the development of dangerous hypotonic bleeding. Fortunately, thanks to the use of modern medications, the risk of these complications is minimal.

Release form and dosage of No-Shpy for pregnant women

Drotaverine is produced by several pharmaceutical companies under different trade names.

The drugs produced are completely similar to each other:

• No-Spa of the Hungarian company Chinoin Pharmaceutical and Chemical Works Co.
• Drotaverine from the Russian pharmaceutical company ALSI Pharma.
• Spasmol from the Russian company Pharmstandard-UfaVITA.
• Spasmonet of the KRKA-Rus company, the Russian branch of the Slovenian company KRKA, and others.

No-Shpa is available in two forms - tablet and injection. The tablets are placed in cardboard packaging, each of which contains one or more blisters. No-Shpa is also available in convenient bottles equipped with a dispenser - when you press the button, one tablet comes out.

In most cases, the standard dose of No-Shpa is 40 mg (1 tablet). A single dose should not exceed 80 mg. This amount is enough to eliminate all unpleasant symptoms within an hour.

The average daily dose of the drug is from 120 to 240 mg, divided into 2-3 doses. According to the instructions for use of No-Shpa during pregnancy, the maximum daily dosage should not exceed 240 mg.

The duration of therapy when taken independently cannot be longer than 1-2 days, since otherwise the risk of side effects increases significantly.

Also, during pregnancy, No-Shpa injections may be prescribed.

Features of using No-Shpa during pregnancy

Although No-Shpa is completely safe for the health of mother and child, it should be used during pregnancy only on the recommendation of an obstetrician-gynecologist. The vast majority of cases of adverse events and overdose occur when taking the drug without permission without prior consultation with a specialist.

If the drug is taken for other medical indications, for example, for the treatment of diseases of the gastrointestinal tract and urinary system, then great care should be taken, since No-Shpa causes systemic relaxation of smooth muscles, including the muscles of the uterus.

In the absence of hypertonicity, it is recommended to choose another treatment for gastroenterological, urological and other diseases. This is especially true in late pregnancy, when excessive relaxation of the uterus with medications can result in premature birth.

Analogues

No-Shpa has many analogues that have antispasmodic and analgesic activity. Although the effects of all these drugs are similar, they have different effects on the fetus and on the mother's body, so you should always consult your doctor before using them.

Analogs of No-Shpa with antispasmodic activity:

There are other equally effective myotropic antispasmodics, however, they should not be taken during pregnancy.

No-Spa is an ideal solution to the problem of abdominal cramps and pain, which combines effectiveness, safety and affordable price. The drug can be purchased at any pharmacy, it does not require special storage conditions and is available without a doctor's prescription. Known for decades, No-Shpa is the most popular drug for the treatment of gastroenterological, urological, obstetric-gynecological and other diseases.

The list of medications that can be used by a woman during pregnancy is quite limited. After all, any substance can have an undesirable effect on a young, completely defenseless organism. No-Spa during pregnancy is one of the few antispasmodics that gently and safely help fight emerging problems.

What is the use of the yellow pill

The drug belongs to the category of mild antispasmodics that can affect smooth muscles. It is effective for:

• intestinal colic;
• renal colic;
• urolithiasis;
• biliary dyskinesia
• gastrointestinal diseases (gastritis, ulcers, colitis).

But the main property for a pregnant woman is the ability of the drug to relieve tone from the muscles of the uterus, thereby reducing the risk of miscarriage. Moreover, it can be used not only at the very beginning of pregnancy, but also at a later stage, right up to childbirth.

Due to the safety of the product, specialists often prescribe No-Shpu during pregnancy for headaches and toothaches. This fact is a real salvation for expectant mothers, since it is very difficult to find a drug that will relieve pain and will not harm the baby.

Do no harm: rules of application

The drug is available not only in the form of tablets, but also as solutions for injection. Depending on the complexity of the situation and the position of the pregnant woman, the doctor may prescribe both No-Shpa injections during pregnancy and taking pills.

Only a specialist can correctly prescribe treatment, so you should strictly follow his instructions. A regular tablet contains 40 mg of active ingredient. Now there are enhanced forms of the drug, in which the concentration of Drotaverine is 80 mg, and they are marked Forte on the packaging.

Often, when No-Shpa injections are administered, painful lumps may appear at the injection site. They usually go away within a few months, but require mandatory monitoring.

As practice shows, pain symptoms disappear after 3–5 days of taking the drug. In this case, the dosage and frequency of administration are set strictly individually. The most common course is 5 days, 1 tablet 3 times a day. To avoid side effects, the medicine should not be taken at a dose of more than 240 mg per day.

If you need to take No-Shpa during pregnancy for toothache or other pain, then it is recommended to take 1-2 tablets precisely at the moment of a painful attack. Next, the cause of the pain should be eliminated, since the drug is not suitable for pregnant women for systematic use.

The best companion in the early stages

It is a generally proven fact that most often beneficial features Drotaverine occurs in the 1st trimester. It is at this stage that an increased tone of the uterus in a pregnant woman is observed.

In the first 12 weeks, the threat of miscarriage is most often diagnosed. In this case, No-Shpa drugs are prescribed in combination with hormonal agents. Their task is to gently and safely supplement the pregnant woman’s body with the missing components and relieve hypertonicity of the muscles in the uterus.

We must not forget that drotaverine is a medicine, so before taking it you should definitely consult a specialist.

Experts can prescribe a course of drotaverine for the entire period of the first trimester, while the fetus is too vulnerable. In this case, it is recommended to drink 1–3 tablets per day. In addition, they can be used as emergency aid. If severe pain appears in the lower abdomen, experts advise taking 2 tablets of No-Shpa and waiting for the ambulance to arrive.

The drug in midterm is not so safe

If in the first 12 weeks experts safely prescribe No-Shpa to all pregnant women, then the 2nd trimester is no longer so loyal. This is due to the peculiarities of pregnancy and hormonal changes.

The fact is that at this stage the baby is already protected by the placenta, which is not only a source of useful components, but also protects it from external influences. Thus, the use of No-Shpa in this case can excessively relax the smooth muscles of the internal organs and the uterus as well. This can lead to premature birth, which should never be allowed.

The break between taking tablets should be at least 6 hours.

In most cases, if a doctor decides to prescribe this drug to a pregnant woman, it will need to be used in a hospital under the supervision of specialists.

No-Shpa as preparation for childbirth

Despite the fact that in the 3rd trimester doctors are also cautious about the drug, sometimes they still prescribe it. This is done in most cases not for the purpose of relieving pain, but, most likely, as preparation for childbirth.

The main task of the drug during this period is:

• softening of the cervix;
• accelerating the process of its opening immediately at the time of birth;
• reduction of pain;
• reducing the risk of perineal ruptures.

It was noted that many women in labor really appreciated the positive effect of using the drug before childbirth. However, doing this on your own just to avoid pain is strictly prohibited and dangerous to health.

If acute pain appears in the lower abdomen, you should take 2 tablets of No-Shpa and give it time to work. If the pain does not go away, this may be the beginning of labor and you should immediately call an ambulance.

Is the drug safe?

Any medical drug, including No-Shpa, has contraindications and side effects. This remedy does not have a selective effect, for example, only on the uterus. It can also relax the muscles of other organs.

A competent specialist will not prescribe drugs based on drotaverine to a pregnant woman if she has the following diseases:

• tendency to allergic reactions;
• pronounced toxicosis;
• increased eye pressure;
• arrhythmia.

The drug contains a certain amount of lactose and galactose, so it should not be taken if there are any problems with the production of gastrointestinal enzymes.

It is noted that while taking Drotaverine, in extremely rare cases, side effects such as nausea, dizziness, constipation and tachycardia may occur. The likelihood of their occurrence is negligible and can only be provoked by excessively exceeding the permissible dosage. That is why No-Shpu is considered safe and can be used during pregnancy.

In the article we discuss No-Shpu during pregnancy. We will tell you whether it can be drunk in the early and late stages, whether the remedy helps with headaches and toothaches, and whether it is effective for uterine tone. You will learn about the recommended dosage of the drug and how to take it in the 1st, 2nd, 3rd trimesters, reviews from pregnant women.

No-Shpa is a round, biconvex tablet of yellowish-orange or yellowish-green color, with “spa” engraved on one side. The active ingredient of the drug is drotaverine - a powerful antispasmodic with myotropic action.

The drug has a direct effect on the smooth muscle fibers located in the walls of the genital organs, as well as the stomach, intestines, uterus, ureter and others. The use of the drug helps to relax the muscular membrane of these organs, eliminate spasms, thereby reducing the intensity of painful sensations or completely disappearing.

No-Shpa is produced in the form of tablets and injection solution

The main advantage of No-shpa compared to other centrally acting muscle relaxants that relieve spasms of smooth muscles is that it does not affect the peripheral and central nervous system. As a result, there are no serious side effects such as respiratory depression due to diaphragmatic paralysis. Due to this, No-shpa is often recommended for use in diseases of the gastrointestinal tract, urological and gynecological in nature, during pregnancy.

Important: due to the systemic effect on smooth muscles, the drug affects the activity of the cardiovascular system. Due to the relaxation of small peripheral vessels, the medication promotes, so it can be taken when. At the same time, such an effect medicine is not very pronounced, and the pressure can drop only after taking large doses.

Compound

The active ingredient of the drug is drotaverine hydrochloride. One tablet contains 40 mg of this component. Additional components:

• magnesium stearate - 3 mg;
• talc - 4 mg;
• povidone - 6 mg;
• corn starch - 35 mg;
• lactose monohydrate - 52 mg.

Forte tablets have the same composition. But with one difference - the concentration of the active substance is 80 mg.

No-Shpa in ampoules contains:

• 20 mg/ml drotaverine hydrochloride;
• 96% ethanol;
• sodium metabisulfite;
• distilled water.

Release form

The drug is available in the form of tablets and solution for injection.

No-Spa tablets:

• blisters of 6 or 24 pieces, one blister in a pack;
• a bottle made of polypropylene, equipped with a piece dispenser, a package of 60 tablets, a bottle in 1 pack.

No-Shpa Forte No. 20 tablets are produced in blister packs of 10 pieces, 2 blisters in one pack.

No-Shpa injections No. 25 (5×5) - one ampoule contains 2 ml of active substance, there are 5 ampoules in one pallet, 5 pallets in a cardboard pack.

These drugs are manufactured by several pharmaceutical companies under different trade names:

• No-Shpa is manufactured by the Hungarian company Chinoin Pharmaceutical and Chemical Works Co.
• Spazmonet is manufactured by KRKA-Rus, which is a Russian branch of the Slovenian company KRKA.
• Spasmol is a domestic manufacturer Pharmstandard-UfaVITA.
• Drotaverine - domestic pharmaceutical company ALSI Pharma.

Where can I buy

You can purchase the drug at a pharmacy. Average prices:

• tablets 6 pcs, 40 mg - from 60 rubles;
• tablets 24 pcs, 40 mg - from 115 rubles;
• ampoules 2 ml, 5 pcs - from 95 rubles;
• ampoules 2 ml, 25 pcs - from 430 rub.

What is it prescribed for?

No-Shpa is recommended in the presence of pathologies that are accompanied by spasm of smooth muscles. Most often it is prescribed for abdominal pain, since it is undesirable to use conventional painkillers in this case.

Indications for use:

• biliary dyskinesia;
• chronic cholecystitis;
• intestinal spasms;
• urolithiasis;
• renal and hepatic colic;
• threat of premature birth;
• cholelithiasis.

In obstetric and gynecological practice, No-Shpu is prescribed for uterine hypertonicity and the risk of premature birth. In some cases, a single dose of the drug at the first symptoms of premature birth or spontaneous abortion, which manifest themselves in the form of nagging pain in the lower abdomen or a feeling of fullness in this area, helps eliminate hypertonicity of the uterus and save the child.

Another indication for the use of No-Shpa is spasm of the smooth muscles of the uterus and cervix during childbirth. This condition is dangerous because the child seems to be squeezed in a vice - the overly tense myometrial muscles are trying to expel him from the uterine cavity, but the contracted cervix does not allow the baby to move along the birth canal. As a rule, the use of one dropper with drotaverine is enough to restore normal labor.

Since the product has an antispasmodic and analgesic effect, it can be used from and. But only if the doctor has given permission to do so.

Before taking No-Shpa, you should read the instructions for use

Benefits and harms

Despite the fact that the drug is safe for the mother and fetus, it can only be taken as prescribed by your doctor. Most of the side effects and other complications after taking No-Shpa occur due to the fact that the pregnant woman herself prescribed this drug and dosage.

If the drug is used not to eliminate uterine hypertonicity or the threat of miscarriage, but for the purpose of treating diseases of the gastrointestinal tract and urinary system, in this case you need to be extremely careful with taking the medicine. This is due to the fact that No-Shpa provokes systemic relaxation of smooth muscles, including the muscles of the uterus.

If there is no hypertonicity, then it is advisable to choose a different drug for the treatment of gastroenterological and urological ailments. This is especially true in the third trimester, when taking the medication can trigger labor ahead of schedule.

Application

The use of the drug during pregnancy has a number of features. Remember, you can drink No-Shpa only after a doctor’s prescription; independent use is prohibited.

In the early stages

In the first trimester, all systems and organs of the unborn child are formed. For this reason, at this time it is recommended to minimize the use of medications and be more attentive to your health.

At this stage, No-Shpu is prescribed for spasms of the smooth muscles of the uterus, since such a condition often leads to miscarriage. The medication helps relax the smooth muscle cells located in the myometrium, restoring its tone. Such conditions are necessary for the full development of the fetus. For this reason, No-Shpu is actively used in the 1st trimester and from 13 to 15 weeks.

In the later stages

In the 2nd and 3rd trimesters, No-Shpu should be used with caution. At this time, the main task of the doctor is to maintain the pregnancy and bring it to physiological terms. For this reason, medications that can provoke labor are not used at all or in very rare cases.

Is No-Shpa dangerous in later stages? It helps to relax the smooth muscles of the uterus, and also has a direct effect on the muscular elements of the cervix. As a result, spontaneous dilatation may occur, which will lead to premature birth. Because of this, antispasmodics are prescribed extremely rarely in the 2nd and 3rd trimesters. As a rule, it is used at 39 weeks of pregnancy.

Before birth

Drotaverine is actively used to facilitate labor, as well as eliminate uterine hypertonicity. Before giving birth, some women in labor are prescribed a standard dosage of No-Shpa during pregnancy to normalize the tone of the uterus and ensure dilation of the cervix. If uterine hypertonicity occurs directly during childbirth, a dropper with drotaverine or an intravenous injection will help to cope with it.

In the third trimester, one of the dangerous side effects of using No-Shpa is uterine hypotension, characterized by delayed separation of the placenta or the formation of hypotonic bleeding. At the same time, most modern medications can reduce the risk of these complications.

Dosage

What dose of No-Shpa is allowed for pregnant women? The standard dosage is 1 tablet (40 mg), but you cannot take more than 80 mg of the drug at a time, that is, two tablets. This amount is enough to eliminate the ailment.

The average daily dosage of the drug is 120-240 mg, which should be divided into 2-3 doses. The instructions for use indicate that the daily dose of No-Shpa during pregnancy should not exceed 240 mg (6 tablets).

When taken independently, the course of treatment cannot be longer than 2 days, otherwise the likelihood of side effects increases.

Also during pregnancy, No-Shpa injections can be prescribed. But injections should only be done by a specialist.

Before using No-Shpa, you should consult your doctor.

Contraindications and side effects

Since the drug affects the smooth muscles of internal organs, in some cases it can cause harm to the body. You should refrain from using it in the following cases:

• Individual intolerance.
• Hypersensitivity to the substances included in the composition. If after taking the medicine there is redness and itching of the skin, a general deterioration in health, swelling of the lips and mouth, then it is prohibited to use it in the future.
• Severe heart failure, arrhythmia - high doses of medication have a negative effect on cardiac activity. For this reason, people with cardiovascular diseases should take the drug with caution and only as prescribed by a specialist.
• Glaucoma - drotaverine tends to increase intraocular pressure, which increases the likelihood of an acute attack of glaucoma and temporary loss of vision in predisposed individuals.

If future mommy suffers from lactase deficiency, as well as other enzymatic disorders of the gastrointestinal tract, in this case you should stop taking No-Shpa in tablet form due to the presence of galactose and lactose in it.

According to statistics, when using No-Shpa, approximately one person out of a thousand experiences side effects, which manifest themselves in the following:

• decreased blood pressure;
• migraine;
• problems with the passage of stool;
• dizziness;
• nausea, in rare cases vomiting.

Typically, such signs occur due to excessive use of the drug to obtain a more lasting analgesic and antispasmodic effect. In most cases, such measures are not necessary, since the recommended dosage of the drug is sufficient to eliminate the ailment.

Overdose

Cases of overdose with drotaverine are quite rare. Most often they occur due to the use of the product without knowing the instructions for use or to accelerate the effect of pain relief.

Signs of overdose:

• general deterioration of health;
• nausea and vomiting;
• problems with stool;
• intestinal obstruction;
• loss of consciousness and severe chest discomfort, which occurs due to severe cardiac conduction disturbances, including the development of atrioventricular block;
• respiratory depression up to its complete stop due to the toxic effect on the respiratory center of the brain.

If the symptoms described above are observed, you need to drink 2-3 glasses of water, then immediately induce artificial vomiting and call an ambulance. Treatment of patients with an overdose of No-Shpa, especially expectant mothers, takes place only in a hospital setting.

Analogues

The drug No-Shpa has many analogues that have an antispasmodic and analgesic effect. Despite the fact that these medications have a similar effect, you should consult a gynecologist before using them, since each drug has a different effect on the body of the pregnant woman and the fetus.

List of myotropic antispasmodics similar to No-Spe, approved during pregnancy:

• Papaverine is prohibited for renal and adrenal insufficiency (more details in the article). Mainly used in surgical practice.
• Sparex, Niaspam, Duspatalin - used in the treatment of intestinal diseases, practically do not cause any harm.